Synthetic approaches to dexmedetomidine
Institute of Organic Chemistry, Catalysis and Petrochemistry, Faculty of Chemical and Food Technology, Slovak University of Technology, Radlinského 9, SK-812 37 Bratislava, Slovak Republic
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Abstract: The review is an attempt at critical evaluation of known synthetic procedures used for laboratory and industrial preparation of a synthetic antihypertensive – Dexmedetomidine as to their complexity, published yield and atom economy.
Keywords: Dexmedetomidine, medetomidine, synthesis, sedatives
Full paper in Portable Document Format: acs_0172.pdf
Acta Chimica Slovaca, Vol. 6, No. 2, 2013, pp. 240—244, DOI: 10.2478/acs-2013-0037