Acta Chimica Slovaca (ACS) publishes papers on fundamental and applied aspects of chemistry, biochemistry, chemical technology, chemical engineering and process control, biotechnology and food technology. Welcome are also topics which include chemical aspects of materials, physical chemistry and chemical physics, analytical chemistry, macromolecular chemistry and biomedical engineering.

Selective solid-phase extraction of phenylcarbamic acid derivatives from a rat serum by molecularly imprinted polymer

Miroslava Lachová *, Jozef Lehotay, Ivan Skačáni, Jozef Čižmárik a

Institute of Analytical Chemistry, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Slovak Republic
a Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Comenius University in Bratislava, Slovak Republic

E-mail: *

Abstract: Molecularly imprinted polymer (MIP) was synthesized using a non-covalent imprinting approach. Methacrylic acid was used as the functional monomer, acetonitrile was used as the porogen and 1-methyl-2-piperidinoethylester of 4-decyloxyphenylcarbamic acid as the imprint molecule (template). Imprinted polymer was utilized as the sorbents for solid-phase extraction (MISPE) to extract derivatives of alkoxyphenylcarbamic acid from spiked rat serum.

Keywords: HPLC, molecularly imprinted polymer, solid-phase extraction

Full paper in Portable Document Format: acs_0016.pdf

Acta Chimica Slovaca, Vol. 1, No. 1, 2008, pp. 175—179