Acta Chimica Slovaca (ACS) publishes papers on fundamental and applied aspects of chemistry, biochemistry, chemical technology, chemical engineering and process control, biotechnology and food technology. Welcome are also topics which include chemical aspects of materials, physical chemistry and chemical physics, analytical chemistry, macromolecular chemistry and biomedical engineering.

Laboratory and industrial synthesis of remifentanil

František Mathia *, Štefan Marchalín, Daniel Végh, Mária Bobošíková, Michaela Halinkovičová

Institute of Organic Chemistry, Catalysis and Petrochemistry, Faculty of Chemical and Food Technology, Slovak University of Technology, Radlinského 9, SK-812 37 Bratislava, Slovak Republic

E-mail: *

Abstract: The submitted review aims at critical evaluation of known synthetic procedures utilized both for laboratory and industrial production of the synthetic analgesic — remifentanil as to their simplicity, published yield and atom economy.

Keywords: remifentanil, synthesis, analgesics

Full paper in Portable Document Format: acs_0122.pdf

Acta Chimica Slovaca, Vol. 5, No. 2, 2012, pp. 145—152